How to avoid the fouling problems of HFF?

Very simple - use a LASER guided diaphragm Single-Use-Pump (SUP) able to repeatedly and super controlled flush out debris, accumulation on the lumen wall of the Hollow-Fibre-Filter (HFF).

 

Complete customizable Process-Control-System able to handle also all the ARC converted to Single-Use-Sensors in a perfusion setup. 
Here a 3.2 litre P-SUB connected to Thalia TM100 which easily keep the HFF clean for the duration of the process.

Check out https://perfusecell.com/products/diaphragm-sups-32

With kind regards from
Per Stobbe