CellRetention™ even at high cell density keep HFF clean in ATF mode
CellRetention is a concept extended from work at customer site late 2017 – mammalian cell cultivated in suspension, cell retention. Broth exchanged forth and back along the HFF by the Thalia Alternating-Single-Use-Pump. CellRetention was originally designed for use in parallel applications - 4 or 8 small P-SUBs for DASbox. All single-use, pre-assembled and ready to use right out of the bag.
The key to the fantastic performance is not the HFF or the SUB - but the LASER guided Thalia A-SUP and by Clotho controlled operation. When any volume and velocity can be programmed and repeated accurately - then the HFF stays clean all through the process !
Check out more details on individual pages.