Mini P-SUB mag-HPD with O-SUP, HFF, SUS for DASbox

World only configurable Perfusion-SUB for TFF operation method offer:

• HFF (Hollow-Fibre-Filter) fouling free process with innovative diaphragm pump
• 100 – 200 ml Working Volume fully pre-assembled P-SUB
• Circulation of broth by Clio-CM80/30 diaphragm OneWay-Single-Use-Pump (O-SUP)

General features of CellMembra™ mini P-SUB designed for DASbox:

• Based on the bioBLU 0.3 batch SUB designed with magnetic HPD for the DASbox
• Fully programmable re-circulated broth volume and velocity, accurately measured and repeatable – no guessing
• Selectable HF – here shown Spectrum/Repligen HFF with pore 0.2 µm, 14 x 1.0 mm straw/lumen, 88 cm² area, Luer-Lok side ports, (D02-P20U-10-N)
• The complete and pre-assembled P-SUB unit packed in dual film bags and precision irradiated – forget the autoclave
• P-SUB dim OD 76 x 120 mm for Working Volume (WV) ranging from 100 ml up to 200 ml though SUS dependent
• Thermal control, agitation, aeration, etc as offered by DASbox
• Clotho communicate via OPC-UA with DasWare

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0.3 BioBLU + Clio CM80 1

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0.3 BioBLU + Clio CM80 2

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0.3 BioBLU + CM80 HFF outlet

Left photo shows bioBLU 0.3 SUB converted to CellMembra-300 P-SUB. Center photo one CellMembra-300 with the blue head plate and visible the latest Clio-CM80/30 SUP. Right photo of CellMembra-300 illustrating the in SUP integrated HFF reducing Luer-Loc shear force.

Further P-SUB mini features:

• Comes with Magnetic HPD as to the DASbox spec
• One free PG13.5 port
• 3 small diameter weldable hoses length 600 mm (upgraded from the 100 mm std)
• 1 short hose with 5 cm² sterile filter for aeration
• 1 short hose with swabable valve for bottom sampling
• 1 exhaust hose with 16 cm² sterile filter

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0.3 BioBLU + Clio CM80 pack

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CellMembra bioBLU dual towers

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HSF OD110 ID76 for DASbox

The CellMembra-300 is heavily equipped with an extensive assembly. Example of how 8 x CellMembra-300 P-SUBs in parallel inserted into the DASbox (for OD 76 mm SUBs). To be operated, controlled by dual Clotho towers and DasWare or directly from the Clotho software independent of DasWare. The pressurized air and vacuum delivered by dual Alagonia and one Sarpedon for each tower. The right photo shows the Heating-Support-Foot allowing the OD76 mm SUB to be used in the ID 110 mm Bioblock.