Small size CellRetention™ keep HFF free from fouling
The 3 liter Perfusion-SUBmerged (P-SUB) is fully assembled, ready to use, operating after the ATF method
SUBmerged 3 liter features:
- 0.4 - 2 liter Working Volume fully pre-assembled P-SUB
- Alternating broth by Thalia diaphragm Alternating-Single-Use-Pump (A-SUP)
- SepraPor C112 HFF (Hollow-Fibre-Filter) with 420 cm2 surface SUBmerged directly into the broth
Benefits are:
- HFF fouling – freedom to select broth velocities flushing out debris from inside the lumen
- Dead volume – skip all the hoses and plastic connectors
- Cell death - inverted Thalia pump above the HFF and P-SUB cannot accumulate cells
- Shear force – remove all hoses and fittings and SUBmerge the HFF into the broth inside the P-SUB
This December - early demo of the 3 liter P-SUB with SUBmerged SepraPor C112 and inverted Thalia TM80 with red LASER support on top. The product name “CellRetention-3-MST” can be found under Commerce. MST explain that the 3 liter P-SUB is mounted in the Heating-Support-Foot (HSF) on the Magnetic-Stirrer-Table (MST). Reason is simple – there is not space for both servo motor, sensors and SUP on head plate. The InCyte biomass seen mounted on the vessel wall.
Industry leading architecture: P-SUBmerged integrates SUB / A-SUP / HFF / SUS with:
- 3.2 liter Vessel-Volume (VV) SUB offer 0.4 – 2 liter Working Volume (WV) in a OD 137 mm vessel
- SUBmerged and integrated HFF with Thalia diaphragm Alternating-Single-Use-Pump (A-SUP)
- SepraPor C112-xx2x with 0.2 µm pore, 55 x 1.0 mm PE straw/lumen, 420 cm2 area, Direct-Fit connection, one permeate side port
- Ground-breaking Thalia LASER sensor guided diaphragm Single-Use-Pump (SUP)
- Single-Use-Sensors (SUS) for DO, pH, bio-mass, temp, level
More information about CellRetention P-SUB to be found under Support