P-SUB integrating Clio diaphragm pump, SepraPor HFF and sensors
World only fully assembled P-SUB for TFF method offer:
- 4 - 10 liter Working Volume (WV) fully pre-assembledP-SUB - no extra assembling in the hood is needed
- SepraPor HFF (Hollow-Fibre-Filter) for fouling free process integrated with innovative LASER guided Clio diaphragm pump
- Broth circulated by Clio diaphragm One-way-Single-Use-Pump(O-SUP) for gentle harvest at low velocity and sequential, instant higher velocity as HFF cleaning pulse
P-SUB 13 liter TFF+HFF+Cronus
Assembly of integrated SUB with Clio CM100 O-SUP and 600 mm long SepraPor HFF. Fully pre-assembled, packed, E-beam irradiated and ready to use as Perfusion-Single-Use-Bioreactor. Flow-chart illustrates most important connections between CellMembra and Cronus-PCS tower.
Industry leading architecture pre-installed P-SUB combining:
- 4 - 10 liter Working Volume fully pre-assembled incl assembly of hoses and bottles
- Circulation of broth by CM100 LASER guided Clio diaphragm OneWay-Single-Use-Pump (O-SUP) driven by Clotho drive unit - gentle harvest and selectable sequential broth velocity for HFF cleaning
- SepraPor HFF C124 (Hollow-Fiber-Filter) cartridge with 932 cm2 surface area integrated into the Clio SUP and SUB - eliminating broth/retentate TRI clamps reducing dead volume
- Single-Use-Sensors (SUS) for DO, pH, bio-mass, temp, level
General specifications for the CellMembra-13 size P-SUB:
- Vessel dimension: OD 200 x 445 mm
- Rigid mono component PolyCarbonate
- 13 liter Vessel Volume (VV) for 4-10 liter Working Volume (WV)
- Thermal control by Electrical-Heating-Blankets
- Head-Plate-Drive (HPD) for selectable servo motors
Single-Use-Sensors (SUS) pre-installed:
- One PG13 port for VisiWell Single-Use-Well (SUW) which fit the VisiFerm
- One PG13 port for pre-installed OneFerm pH Single-Use-Sensor (SUS)
- InCyte ARC bio-mass sensor patch installed in wall close to bottom
- One port for thermo couple
- level sensors as needed
- extra PG13.5 port