Revolutionizing TFF-Integrated bioreactor - series 30
CellMembra™ P-SUBs cultivate mammalian cells lines reliable at high density via TFF-Integrated for weeks.
Benefits of TFF-Integrated are:
- avoid HFF fouling – freedom to select any broth velocity flushing out debris inside HFF by LASER guided Clio diaphragm pump
- avoid dead volumes – skip hoses, fittings - Integrated SepraPor HFF with Clio diaphragm pump reduces dead volumes
- reduce shear stress – eliminating hoses, fittings and Integrated directly with Clio pump reduces shear stress to lowest possible
Flush easily out fouling, debris from inside the HFFs lumen
CellMembra present range of scalable P-SUBs fully pre-assembled integrating 0.2 µm pore size SepraPor Hollow-Fiber-Filter and Clio diaphragm Single-Use-Pump into a unique assembly driving the perfusion process. The unique super compact Clotho diaphragm pump Drive Unit in center of photos.
CellMembra TFF-Integrated is a range of cultivation system sizes integrating all the components. The Perfusion-Single-Use-Bioreactor (P-SUB) integrates the unique Clio diaphragm One-way-Single-Use-Pump (O-SUP) with the SepraPor Hollow-Fiber-Filter (HFF) and Hamilton Single-Use-Sensors (SUS). The unique Clio O-SUP is designed to flush out debris keeping the HFF clean even in TFF mode.
Customizable CellMembra TFF-Integrated portfolio (series 30):
- 80 - 150 ml P-SUB Working Volume (WV) - 300 ml Vessel Volume (VV) - for DASbox
- 100 - 350 ml P-SUB Working Volume (WV) - 500 ml VV - for Cronus-PCS or most PCS
- 0.4 - 2 litre P-SUB Working Volume (WV) - 3 liter VV - for Cronus-PCS or most PCS
- 4 - 10 liter P-SUB Working Volume (WV) - 13 liter VV - ultimo 2026 - for Cronus-PCS or most PCS
All pre-assembled, pre-packed, all single-use (of course) and ready for reliable cultivation. Work with most Process-Control-Systems.