Scalable diaphragm Single-Use-Pumps for perfusion - series 35

One of the purposes of the CerPhragm family of Single-Use-Pumps (SUP) is to facilitate upstream perfusion cultivation and secure a single Hollow-Fiber-Filter (HFF) stays clean for the entire process. Two variants of the LASER guided CerPhragm family of diaphragm SUPs is available:

• ATF operation method – Alternating-Tangential-Flow - pump named Thalia = A-SUP with no valves - Thalia unifies with the HFF and SUB into the CellRetention ATF-SUBmerged principle

• TFF operation method – Tangential-Flow-Filtration - pump named Clio = O-SUP with 2 integrated passive valves ensure OneWay flow direction = Clio integrates with the HFF and SUB into the CellMembra TFF-Integrated principle

Both Thalia and Clio SUPs offer un-precedented and gentle performance guided by a LASER and controlled by either of Clotho or Lachesis or Atropos Drive Units. Here shown Thalia SUPs and super customized HFF from Meissner Corp.

SepraPor HFF unified with Thalia or Clio SUPs is revolutionizing. Both SUPs keep the HFF clean and free from fouling. This valuable benefit is fully programable with selectable low broth velocity for gentle harvest and sequential higher velocity flushing out debris for optimum process time. 

 

Clio is available as stand-alone version for various uses – see separate page.

The CerPhragm "Single-Use-Pump" family (Thalia and Clio) are, as the expression indicates, made entirely from polymers and as such not designed to be high temperature autoclaved. Supplied E-beam irradiated in dual foil bags. 

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