Mini P-SUB mag-HPD with O-SUP, HFF, SUS for DASbox
World only configurable mini Perfusion-SUB for TFF operation method offer:
- HFF (SepraPor Hollow-Fibre-Filter) fouling free process with innovative diaphragm pump
- 100 – 200 ml Working Volume fully pre-assembled P-SUB
- Circulation of broth by Clio-CM80/30 diaphragm OneWay-Single-Use-Pump (O-SUP)
General features of CellMembra™ mini P-SUB (ver-10) designed for DASbox:
- Based on the BioBLU 0.3 batch SUB designed with magnetic HPD for the DASbox
- Fully programmable re-circulated broth volume and velocity, accurately measured and repeatable – no guessing
- SepraPor® HFF with pore 0.2 µm, 1.0 mm straw/lumen, 110 cm2 area, barb side ports
- The complete and pre-assembled P-SUB unit packed in dual film bags and precision irradiated – forget the autoclave
- P-SUB dim OD 76 x 120 mm for Working Volume (WV) ranging from 100 ml up to 200 ml though SUS dependent
- Thermal control, agitation, aeration, etc as offered by DASbox
- Clotho communicate via OPC-UA
Left photo shows BioBLU 0.3 SUB converted to CellMembra-300 P-SUB. Center photo one CellMembra-300 (ver-10) with the blue head plate and visible the latest Clio-CM80/40 SUP. Right photo of CellMembra-300 illustrating the in SUP integrated HFF eliminating Luer-Loc hereby reducing Luer-Loc caused shear force significant.
Further P-SUB mini features:
- Comes with Magnetic HPD as to the DASbox spec with Maxon motor
- One free PG13.5 port
- 3 small diameter weldable hoses length 600 mm (upgraded from the 100 mm std)
- 1 short hose with 5 cm2 sterile filter for aeration
- 1 short hose with swabable valve for bottom sampling
- 1 exhaust hose with 16 cm2 sterile filter
The CellMembra-300 as delivered dual bag packed and E-beam irradiated. Heavily equipped with an extensive assembly ready to install and use. Example of how CellMembra-300 P-SUBs in parallel inserted into the DASbox (originally designed for OD 76 mm STR). Right photo show ver-8 including the PICO when available.
Flow-Chart illustrates the setup with Clotho Tower (in the yellow box) operating the LASER controlled Clio SUP, keep an eye on the TMP and ensure regular cleaning of the HFF. Center photo 8 P-SUBs in parallel. operated, controlled by dual Clotho towers and DasWare or directly from the Clotho software also independent of DasWare. The pressurized air and vacuum delivered by dual Alagonia and one Sarpedon for each tower. A photo of a lot in production.