It’s all about knowing where we are at any time
Some years back we were in a desperate need for the absolutely optimum pump to be integrated with continuous processing bioreactor systems. Old fashion peristaltic and centrifugal pumps was out of the question! Diaphragm pumps sounded great – but none such accurately controlled diaphragm pump existed! Combined with single-use capability and low cost … we had to develop and patent this pump ourselves!
Quite appropriate “Clotho” is the Greek goodness of life time and one of the 3 fates, which combined control life of every mortal from birth to death. There were 3 Moirai goodness’s and the two other sisters are “Atropos” and “Lachesis”. Clotho measures the “thread of life”, which makes good sense for determining the process of a continuous operating bioreactor!
The concept of regulating dynamically / in real-time the position of a free-floating elastic membrane is miles ahead of any traditional membrane / diaphragm pump / exchanger. The invention originated from the CEO of PerfuseCell and the concept is visible via the patent application WO2010/069321 year 2010.