Keep HFF clean - integrated with diaphragm pump and SUB

Perfusion-Single-Use-Bioreactor = P-SUB

PerfuseCell™ customize and manufacture a variety of fully equipped Perfusion-Single-Use-Bioreactor's for cultivating mammalian cells at high cell density for expression of proteins, antibodies, vaccines.

Key unique benefits of CellRetention in the SUBmerged design are:

  • HFF fouling – freedom to select broth velocities flushing out debris from inside the lumen
  • Dead volumes – skip all the hoses and plastic connectors, SUBmerge and integrate the HFF 100 % with Thalia diaphragm pump
  • SUBmerged - the HFF inlet arranged SUBmerged in the broth inside the SUB
  • Cell death - inverted Thalia pump above the HFF and SUB cannot accumulate cells 
  • Shear force – remove all hoses and fittings and SUBmerge the HFF into the SUB
Cellmembra Mini And Clotho Controller2023 Thalia 3200 P SUB02023 Thalia Incyte PSUB2023 10 26 Perfusecell Cronus PCS Setup

Fully assembled P-SUBs with Vessel Volume (VV) ranging from 0.3 for DASbox or 250 ml for the Modular PCS scalable further from 0.5 - 3.2 - 5.7 - 13 up to 30 liter.

The key for cleaning and keep the Hollow-Fibre-Filter's clean in any of our P-SUBs is the LASER guided diaphragm Single-Use-Pump's (SUP) Thalia or Clio able to alter accurately fluid velocities flushing out fouling.
 

  1. CellRetention™ (series 31) operate in ATF mode and integrate the scalable Thalia Alternating-Single-Use-Pump (A-SUP) with the SepraPor™ Hollow-Fiber-Filter module, and a range of Single-Use-Sensor's. The unique SUBmerged design is pre-assembled, pre-packed and ready for easy use with our pump Drive Unit's. Eliminating the restricting TRI-clamp or Sanitary clamps with Direct-Fit HFF
  2. CellMembra™ (series 30) operate in TFF mode and integrate the scalable Clio OneWay-Single-Use-Pump (O-SUP) with the SepraPor™ Hollow-Fiber-Filter module, and multiple Single-Use-Sensor's. All pre-assembled, pre-packed and ready for easy use with our pump Drive Unit's. Eliminating the restricting TRI-clamp, Luer-Loc with Direct-Fit HFF
  3. If you need the Thalia A-SUP (series 32) pre-assembled with large SepraPor™ HFF scaling from 50 liter and up to 500 liter - ask us -
  4. Drive Units Clotho and Lachesis (series 33) for Thalia and Clio with AI designed software. Our P-SUBs also runs perfect on Cronus-PCS via Lucullus or DeltaV software.

Patents applied for or issued for all products - check out Intellectual Property Rights

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